أدريسين

MADCAM1
التراكيب المتوفرة
بنك بيانات البروتين	Human UniProt search: PDBe RCSB
قائمة رموز معهدات بنك بيانات البروتين
	1BQS, 1GSM, 4HBQ, 4HC1, 4HCR, 4HD9
المعهدات
الأسماء المستعارة	MADCAM1, MACAM1, mucosal vascular addressin cell adhesion molecule 1
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 102670 GeneCards: 8174
فهم الوجود الجيني
الوظيفة الجزيئية	• integrin binding involved in cell-matrix adhesion;
المكونات الخلوية	• مكون تكاملي للغشاء; • غشاء خلوي; • غشاء;
العمليات الحيوية	• leukocyte tethering or rolling; • heterotypic cell-cell adhesion; • التصاق الخلايا; • cell-matrix adhesion; • extracellular matrix organization; • receptor clustering; • استجابة مناعة; • توصيل الإشارة; • regulation of immune response; • positive regulation of leukocyte migration; • integrin-mediated signaling pathway; • positive regulation of lymphocyte migration;
	المصادر:Amigo / QuickGO
أورثولوج
	Q13477
	n/a
	‏NM_130760 NM_130762، ‏NM_130760
	n/a
	‏NP_570118 NP_570116، ‏NP_570118
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

الأدريسين‏ (Mucosal vascular addressin cell adhesion molecule 1) هوَ بروتين يُشَفر بواسطة جين Addressin في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Al-Qamoos القاموس - English Arabic dictionary / قاموس إنجليزي عربي". www.alqamoos.org. مؤرشف من الأصل في 24 فبراير 2019. اطلع عليه بتاريخ 24 فبراير 2019.
^ Leung E, Berg RW, Langley R, Greene J, Raymond LA, Augustus M, Ni J, Carter KC, Spurr N, Choo KH, Krissansen GW (1997). "Genomic organization, chromosomal mapping, and analysis of the 5' promoter region of the human MAdCAM-1 gene". Immunogenetics. 46 (2): 111–9. doi:10.1007/s002510050249. PMID 9162097.
^ "Entrez Gene: mucosal vascular addressin cell adhesion molecule 1". مؤرشف من الأصل في 05 ديسمبر 2010.
^ Addressin at إي ميديسين Dictionary نسخة محفوظة 01 ديسمبر 2016 على مسقط واي باك مشين.
^ Shyjan AM, Bertagnolli M, Kenney CJ, Briskin MJ (أبريل 1996). "Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha أربعة beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences". J. Immunol. 156 (8): 2851–7. PMID 8609404.

قراءة متعمقة

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Tan K, Casasnovas JM, Liu JH, et al. (1998). "The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition". Structure. 6 (6): 793–801. doi:10.1016/S0969-2126(98)00080-X. PMID 9655832.
de Château M, Chen S, Salas A, Springer TA (2001). "Kinetic and mechanical basis of rolling through an integrin and novel Ca2+-dependent rolling and Mg2+-dependent firm adhesion modalities for the alpha أربعة beta 7-MAdCAM-1 interaction". Biochemistry. 40 (46): 13972–9. doi:10.1021/bi011582f. PMID 11705388.
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