HCLS1

HCLS1
المعهدات
الأسماء المستعارة	HCLS1, CTTNL, HS1, lckBP1, p75, hematopoietic cell-specific Lyn substrate 1
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 601306 MGI: MGI:104568 HomoloGene: 38034 GeneCards: 3059
فهم الوجود الجيني
الوظيفة الجزيئية	• RNA polymerase II transcription factor binding; • SH3 domain binding; • ‏GO:0001948 ربط بروتيني; • actin binding; • protein kinase binding; • ‏GO:0032403 macromolecular complex binding;
المكونات الخلوية	• سيتوبلازم; • غشاء; • transcription factor complex; • ميتوكندريون; • نواة; • عصارة خلوية; • غشاء خلوي;
العمليات الحيوية	• positive regulation of protein kinase B signaling; • intracellular signal transduction; • ضبط نسخ الدنا; • positive regulation of tyrosine phosphorylation of STAT protein; • positive regulation of macrophage differentiation; • negative regulation of transcription from RNA polymerase II promoter; • cellular response to cytokine stimulus; • positive regulation of peptidyl-serine phosphorylation; • regulation of actin filament polymerization; • actin filament polymerization; • ضبط زيادي للتكاثر الخلوي; • positive regulation of peptidyl-tyrosine phosphorylation; • positive regulation of granulocyte differentiation; • erythrocyte differentiation; • negative regulation of leukocyte apoptotic process; • response to hormone; • positive regulation of phosphatidylinositol 3-kinase signaling; • positive regulation of actin cytoskeleton reorganization; • ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني; • positive regulation of protein import into nucleus; • positive regulation of sequence-specific DNA binding transcription factor activity;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	; ;
	المزيد من بيانات التعبير المرجعية
أورثولوج
	P14317
	P49710
	‏NM_001292041 NM_005335، ‏NM_001292041
	NM_008225
	‏NP_005326 NP_001278970، ‏NP_005326
	NP_032251
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

HCLS1‏ (Hematopoietic cell-specific Lyn substrate 1) هوَ بروتين يُشَفر بواسطة جين HCLS1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ Egashira M, Kitamura D, Watanabe T, Niikawa N (Jan 1997). "The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization". Cytogenet Cell Genet. 72 (2–3): 175–6. doi:10.1159/000134179. PMID 8978766.
^ "Entrez Gene: HCLS1 hematopoietic cell-specific Lyn substrate 1". مؤرشف من الأصل في 05 ديسمبر 2010.
^ van Rossum AG, Schuuring-Scholtes E, van Buuren-van Seggelen V, Kluin PM, Schuuring E (Mar 2005). "Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain". BMC Genomics. 6: 15. doi:10.1186/1471-2164-6-15. PMC 554100. PMID 15710041.

قراءة متعمقة

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