الوراثة المندلية البشرية عبر الإنترنت 167413 MGI: MGI:97488 HomoloGene: 4515 GeneCards: 5078
فهم الوجود الجيني
الوظيفة الجزيئية
• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • ربط دي إذا إي • sequence-specific DNA binding • GO:0001078، GO:0001214، GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • double-stranded DNA binding • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001948 ربط بروتيني
المكونات الخلوية
• بلازم نووي • نواة
العمليات الحيوية
• تمايز خلوي • ضبط نسخ الدنا • negative regulation of apoptotic process • negative regulation of transcription from RNA polymerase II promoter • نسخ الدنا • نمومتعدد الخلايا • retina development in camera-type eye • نظم يوماوي • positive regulation of cell differentiation • تشكل العضوالحيواني • regulation of cell differentiation • response to cAMP • negative regulation of transcription, DNA-templated • response to drug • endocrine pancreas development • pancreas development
PAX4 (Paired box 4) هوَ بروتين يُشَفر بواسطة جين PAX4 في الإنسان.
الوظيفة
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
الأهمية السريرية
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
المراجع
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^"Entrez Gene: PAX4 paired box gene 4". مؤرشف من الأصل فيسبعة مارس 2010.
^Matsushita T, Yamaoka T, Otsuka S, Moritani M, Matsumoto T, Itakura M (Jan 1998). "Molecular cloning of mouse paired-box-containing gene (Pax)-4 from an islet beta cell line and deduced sequence of human Pax-4". Biochemical and Biophysical Research Communications. 242 (1): 176–80. doi:10.1006/bbrc.1997.7935. PMID 9439631.
قراءة متعمقة
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Matsushita T, Yamaoka T, Otsuka S, Moritani M, Matsumoto T, Itakura M (Jan 1998). "Molecular cloning of mouse paired-box-containing gene (Pax)-4 from an islet beta cell line and deduced sequence of human Pax-4". Biochemical and Biophysical Research Communications. 242 (1): 176–80. doi:10.1006/bbrc.1997.7935. PMID 9439631.
Inoue H, Nomiyama J, Nakai K, Matsutani A, Tanizawa Y, Oka Y (Feb 1998). "Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue". Biochemical and Biophysical Research Communications. 243 (2): 628–33. doi:10.1006/bbrc.1998.8144. PMID 9480859.
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تاريخ النشر:
2020-06-02 13:02:11
التصنيفات:
جينات على كروموسوم 7, عوامل نسخ, صفحات تستعمل قالبا ببيانات مكررة, مقالات بها أقسام فارغة منذ يوليو 2018, جميع المقالات التي بها أقسام فارغة, صفحات بها بيانات ويكي بيانات, صفحات تستخدم خاصية P639, معرفات مركب كيميائي, بوابة الكيمياء الحيوية/مقالات متعلقة, بوابة طب/مقالات متعلقة, بوابة علم الأحياء الخلوي والجزيئي/مقالات متعلقة, جميع المقالات التي تستخدم شريط بوابات, جميع مقالات البذور, بذرة جين على كروموسوم 7