BOP1

BOP1
المعهدات
الأسماء المستعارة	BOP1, block of proliferation 1, ribosomal biogenesis factor
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 610596 MGI: MGI:1334460 HomoloGene: 6612 GeneCards: 23246
فهم الوجود الجيني
الوظيفة الجزيئية	• ribonucleoprotein complex binding; • ‏GO:0001948 ربط بروتيني; • RNA binding;
المكونات الخلوية	• نوية; • نواة; • PeBoW complex; • بلازم نووي; • preribosome, large subunit precursor; • ribonucleoprotein;
العمليات الحيوية	• ribosomal large subunit biogenesis; • cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • cellular proliferation; • ribosome biogenesis; • regulation of cell cycle; • rRNA processing; • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • ribosomal large subunit assembly; • regulation of signal transduction by p53 class mediator; • maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	; ;
	المزيد من بيانات التعبير المرجعية
أورثولوج
	Q14137
	P97452
	NM_015201
	NM_013481
	NP_056016
	NP_038509
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

BOP1‏ (Block of proliferation 1) هوَ بروتين يُشَفر بواسطة جين BOP1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ Nagase T, Seki N, Tanaka A, Ishikawa K, Nomura N (Mar 1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. doi:10.1093/dnares/2.4.167. PMID 8590280.
^ "Entrez Gene: BOP1 block of proliferation 1". مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

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Pestov DG, Stockelman MG, Strezoska Z, Lau LF (2001). "ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAs". Nucleic Acids Res. 29 (17): 3621–30. doi:10.1093/nar/29.17.3621. PMC 55883. PMID 11522832.
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