RAB8A

RAB8A
التراكيب المتوفرة
بنك بيانات البروتين	Ortholog search: PDBe RCSB
قائمة رموز معهدات بنك بيانات البروتين
	3QBT, 3TNF, 4LHV, 4LHW, 4LHX, 4LHY, 4LHZ, 4LI0
المعهدات
الأسماء المستعارة	RAB8A, MEL, RAB8, member RAS oncogene family
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 165040 MGI: MGI:96960 HomoloGene: 100934 GeneCards: 4218
فهم الوجود الجيني
الوظيفة الجزيئية	• nucleotide binding; • GDP binding; • GTP binding; • Rab GTPase binding; • myosin V binding; • ‏GO:0001948 ربط بروتيني; • protein kinase binding; • GTPase activity;
المكونات الخلوية	• سيتوبلازم; • ciliary basal body; • recycling endosome; • عصارة خلوية; • جسيم داخلي; • جسيم مركزي; • phagocytic vesicle membrane; • جهاز غولجي; • إسقاط خلية; • غشاء; • كثافة بعد المشبكي; • حويصلة تشابكية; • Golgi membrane; • هدب; • ciliary base; • neuronal cell body; • تغصن; • phagocytic vesicle; • مريكز; • extracellular exosome; • هيكل خلوي; • حويصلة سيتوبلازمية; • نسيج خارج الخلية; • غشاء خلوي; • trans-Golgi network transport vesicle; • trans-Golgi network membrane; • dendritic spine; • recycling endosome membrane; • non-motile cilium; • secretory granule membrane; • midbody; • تشابك عصبي; • glutamatergic synapse;
العمليات الحيوية	• regulation of long-term neuronal synaptic plasticity; • regulation of protein transport; • axonogenesis; • vesicle docking involved in exocytosis; • protein secretion; • regulation of protein localization; • cell projection organization; • G2/M transition of mitotic cell cycle; • Golgi vesicle fusion to target membrane; • protein transport; • protein localization to plasma membrane; • cellular response to insulin stimulus; • cilium morphogenesis; • ciliary basal body docking; • neurotransmitter receptor transport to postsynaptic membrane; • regulation of autophagy; • التهام ذاتي; • تعديل ما بعد الترجمة; • regulation of exocytosis; • نقل; • intracellular protein transport; • Rab protein signal transduction; • neurotransmitter receptor transport, endosome to postsynaptic membrane; • vesicle-mediated transport in synapse;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	P61006; A0A024R7I3
	P55258
	NM_005370
	NM_023126
	NP_005361; NP_005361.2
	NP_075615
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

RAB8A‏ (RAB8A, member RAS oncogene family) هوَ بروتين يُشَفر بواسطة جين RAB8A في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Entrez Gene: RAB8A RAB8A, member RAS oncogene family". مؤرشف من الأصل في 05 ديسمبر 2010.
^ Huber LA, Pimplikar S, Parton RG, Virta H, Zerial M, Simons K (Oct 1993). "Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane". The Journal of Cell Biology. 123 (1): 35–45. doi:10.1083/jcb.123.1.35. PMC 2119815. PMID 8408203.
^ Nimmo ER, Sanders PG, Padua RA, Hughes D, Williamson R, Johnson KJ (Aug 1991). "The MEL gene: a new member of the RAB/YPT class of RAS-related genes". Oncogene. 6 (8): 1347–51. PMID 1886711.

قراءة متعمقة

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