EGLN2

EGLN2
المعهدات
الأسماء المستعارة	EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 606424 MGI: MGI:1932287 HomoloGene: 14204 GeneCards: 112398
فهم الوجود الجيني
الوظيفة الجزيئية	• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; • L-ascorbic acid binding; • ربط أيون الحديد; • dioxygenase activity; • ربط أيون فلزي; • ‏GO:0001948 ربط بروتيني; • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; • oxidoreductase activity; • ferrous iron binding; • oxygen sensor activity; • peptidyl-proline 4-dioxygenase activity;
المكونات الخلوية	• بلازم نووي; • نواة;
العمليات الحيوية	• response to hypoxia; • positive regulation of protein catabolic process; • regulation of neuron apoptotic process; • peptidyl-proline hydroxylation to 4-hydroxy-L-proline; • cell redox homeostasis; • regulation of cell growth; • regulation of transcription from RNA polymerase II promoter in response to hypoxia; • oxidation-reduction process; • intracellular estrogen receptor signaling pathway;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	Q96KS0; M0R350
	Q91YE2
	‏NM_017555، ‏NM_053046 NM_080732، ‏NM_017555، ‏NM_053046
	‏NM_001357767، ‏XM_030241989، ‏XM_030241990، ‏XM_030241991 NM_053208، ‏NM_001357767، ‏XM_030241989، ‏XM_030241990، ‏XM_030241991
	‏NP_542770 NP_444274، ‏NP_542770
	‏NP_001344696، ‏XP_030097849، ‏XP_030097850، ‏XP_030097851 NP_444438، ‏NP_001344696، ‏XP_030097849، ‏XP_030097850، ‏XP_030097851
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

EGLN2‏ (Egl-9 family hypoxia inducible factor 2) هوَ بروتين يُشَفر بواسطة جين EGLN2 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Entrez Gene: EGLN2 egl nine homolog 2 (C. elegans)". مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

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