EIF2B1

EIF2B1
التراكيب المتوفرة
بنك بيانات البروتين	Ortholog search: PDBe RCSB
قائمة رموز معهدات بنك بيانات البروتين
	3ECS
المعهدات
الأسماء المستعارة	EIF2B1, EIF2B, EIF2BA, eukaryotic translation initiation factor 2B subunit alpha
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 606686 MGI: MGI:2384802 HomoloGene: 1080 GeneCards: 1967
فهم الوجود الجيني
الوظيفة الجزيئية	• translation initiation factor activity; • guanyl-nucleotide exchange factor activity; • ‏GO:0001948 ربط بروتيني; • identical protein binding;
المكونات الخلوية	• سيتوبلازم; • عصارة خلوية; • غشاء; • غشاء خلوي; • Eukaryotic initiation factor 2B;
العمليات الحيوية	• response to peptide hormone; • response to heat; • response to glucose; • cell metabolism; • oligodendrocyte development; • اصطناع حيوي للبروتين; • translational initiation; • T cell receptor signaling pathway; • regulation of translational initiation;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	Q14232
	Q99LC8
	NM_001414
	‏XM_006530275 NM_145371، ‏XM_006530275
	NP_001405
	‏XP_006530338 NP_663346، ‏XP_006530338
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

EIF2B1‏ (Eukaryotic translation initiation factor 2B subunit alpha) هوَ بروتين يُشَفر بواسطة جين EIF2B1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Entrez Gene: EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa". مؤرشف من الأصل فيستة مارس 2010.

قراءة متعمقة

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Welsh GI, Miyamoto S, Price NT, Safer B, Proud CG (1996). "T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3". J. Biol. Chem. 271 (19): 11410–3. doi:10.1074/jbc.271.19.11410. PMID 8626696.
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van der Knaap MS, van Berkel CG, Herms J, van Coster R, Baethmann M, Naidu S, Boltshauser E, Willemsen MA, Plecko B, Hoffmann GF, Proud CG, Scheper GC, Pronk JC (2004). "eIF2B-Related Disorders: Antenatal Onset and Involvement of Multiple Organs". Am. J. Hum. Genet. 73 (5): 1199–207. doi:10.1086/379524. PMC 1180499. PMID 14566705.
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