LILRA1

LILRA1
المعهدات
الأسماء المستعارة	LILRA1, CD85I, LIR-6, LIR6, leukocyte immunoglobulin like receptor A1
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 604810 HomoloGene: 134026 GeneCards: 11024
فهم الوجود الجيني
الوظيفة الجزيئية	• antigen binding; • transmembrane signaling receptor activity;
المكونات الخلوية	• مكون تكاملي للغشاء; • غشاء خلوي; • غشاء;
العمليات الحيوية	• defense response; • سبيل إشارات مستقبلات سطح الخلية; • adaptive immune response; • regulation of immune response; • immune system process;
	المصادر:Amigo / QuickGO
أورثولوج
	O75019
	n/a
	‏NM_001278319، ‏NM_006863، ‏NR_103501، ‏NR_103502، ‏NR_103503 NM_001278318، ‏NM_001278319، ‏NM_006863، ‏NR_103501، ‏NR_103502، ‏NR_103503
	n/a
	‏NP_001265248، ‏NP_006854 NP_001265247، ‏NP_001265248، ‏NP_006854
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

LILRA1‏ (Leukocyte immunoglobulin like receptor A1) هوَ بروتين يُشَفر بواسطة جين LILRA1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Entrez Gene: Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1". مؤرشف من الأصل في 15 فبراير 2017.

قراءة متعمقة

Allen RL, Raine T, Haude A, Trowsdale J, Wilson MJ (November 2001). "Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures". Journal of Immunology. 167 (10): 5543–7. doi:10.4049/jimmunol.167.10.5543. PMID 11698424.
Tedla N, Lee CW, Borges L, Geczy CL, Arm JP (February 2008). "Differential expression of leukocyte immunoglobulin-like receptors on cord-blood-derived human mast cell progenitors and mature mast cells". Journal of Leukocyte Biology. 83 (2): 334–43. doi:10.1189/jlb.0507314. PMID 17998301.
Wilson MJ, Torkar M, Haude A, Milne S, Jones T, Sheer D, Beck S, Trowsdale J (April 2000). "Plasticity in the organization and sequences of human KIR/ILT gene families". Proceedings of the National Academy of Sciences of the United States of America. 97 (9): 4778–83. doi:10.1073/pnas.080588597. PMC 18309. PMID 10781084.
Brown D, Trowsdale J, Allen R (September 2004). "The LILR family: modulators of innate and adaptive immune pathways in health and disease". Tissue Antigens. 64 (3): 215–25. doi:10.1111/j.0001-2815.2004.00290.x. PMID 15304001.
Tedla N, An H, Borges L, Vollmer-Conna U, Bryant K, Geczy C, McNeil HP (April 2011). "Expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium: correlations to disease activity". Tissue Antigens. 77 (4): 305–16. doi:10.1111/j.1399-0039.2011.01633.x. PMID 21388353.
Pilsbury LE, Allen RL, Vordermeier M (2010). "Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection". Mediators of Inflammation. 2010: 536478. doi:10.1155/2010/536478. PMC 2903975. PMID 20634939.
Borges L, Hsu ML, Fanger N, Kubin M, Cosman D (December 1997). "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules". Journal of Immunology. 159 (11): 5192–6. PMID 9548455.
Ryu M, Chen Y, Qi J, Liu J, Fan Z, Nam G, Shi Y, Cheng H, Gao GF (April 2011). Kanellopoulos J (المحرر). "LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence". PLoS One. 6 (4): e19245. doi:10.1371/journal.pone.0019245. PMC 3084784. PMID 21559424.
Wang KS, Liu X, Aragam N, Mullersman JE, Jian X, Pan Y, Liu Y (February 2012). "Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence". Journal of Molecular Neuroscience. 46 (2): 265–71. doi:10.1007/s12031-011-9530-6. PMID 21547531.