• positive regulation of actin filament polymerization • negative regulation of ruffle assembly • actin filament organization • nervous system development • axon guidance • سبيل إشارات مستقبلات سطح الخلية • تشكل العضوالحيواني • actin polymerization or depolymerization • protein homotetramerization • negative regulation of epithelial cell migration • positive regulation of stress fiber assembly • actin nucleation • cellular response to interferon-gamma
Enah/Vasp-like (Enah/Vasp-like) هوَ بروتين يُشَفر بواسطة جين Enah/Vasp-like في الإنسان.
الوظيفة
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
الأهمية السريرية
هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.
المراجع
^"Entrez Gene: EVL Enah/Vasp-like". مؤرشف من الأصل في 05 ديسمبر 2010.
^Klostermann A, Lutz B, Gertler F, Behl C (Jan 2001). "The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain". J Biol Chem. 275 (50): 39647–53. doi:10.1074/jbc.M006316200. PMID 10993894.
^Lambrechts A, Kwiatkowski AV, Lanier LM, Bear JE, Vandekerckhove J, Ampe C, Gertler FB (Dec 2000). "cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains". J Biol Chem. 275 (46): 36143–51. doi:10.1074/jbc.M006274200. PMID 10945997.
قراءة متعمقة
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Krause M, Sechi AS, Konradt M, et al. (2000). "Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton". J. Cell Biol. 149 (1): 181–94. doi:10.1083/jcb.149.1.181. PMC 2175102. PMID 10747096.
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Scott MP, Zappacosta F, Kim EY, et al. (2002). "Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1". J. Biol. Chem. 277 (31): 28238–46. doi:10.1074/jbc.M202783200. PMID 12029088.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Salazar MA, Kwiatkowski AV, Pellegrini L, et al. (2004). "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton". J. Biol. Chem. 278 (49): 49031–43. doi:10.1074/jbc.M308104200. PMID 14506234.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Krause M, Leslie JD, Stewart M, et al. (2004). "Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics". Dev. Cell. 7 (4): 571–83. doi:10.1016/j.devcel.2004.07.024. PMID 15469845.
Lafuente EM, van Puijenbroek AA, Krause M, et al. (2004). "RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion". Dev. Cell. 7 (4): 585–95. doi:10.1016/j.devcel.2004.07.021. PMID 15469846.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rotter B, Bournier O, Nicolas G, et al. (2005). "AlphaII-spectrin interacts with Tes and EVL, two actin-binding proteins located at cell contacts". Biochem. J. 388 (Pt 2): 631–8. doi:10.1042/BJ20041502. PMC 1138971. PMID 15656790.
Barzik M, Kotova TI, Higgs HN, et al. (2005). "Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins". J. Biol. Chem. 280 (31): 28653–62. doi:10.1074/jbc.M503957200. PMC 1747414. PMID 15939738.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Bournier O, Kroviarski Y, Rotter B, et al. (2006). "Spectrin interacts with EVL (Enabled/vasodilator-stimulated phosphoprotein-like protein), a protein involved in actin polymerization". Biol. Cell. 98 (5): 279–93. doi:10.1042/BC20050024. PMID 16336193.
Bausen M, Fuhrmann JC, Betz H, O'sullivan GA (2006). "The state of the actin cytoskeleton determines its association with gephyrin: role of ena/VASP family members". Mol. Cell. Neurosci. 31 (2): 376–86. doi:10.1016/j.mcn.2005.11.004. PMID 16376568.
تاريخ النشر:
2020-06-02 13:11:26
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