GNGT1

GNGT1
المعهدات
الأسماء المستعارة	GNGT1, GNG1, G protein subunit gamma transducin 1
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 189970 MGI: MGI:109165 HomoloGene: 7738 GeneCards: 2792
فهم الوجود الجيني
الوظيفة الجزيئية	• ‏GO:0001948 ربط بروتيني; • signal transducer activity; • GTPase activity; • G-protein beta-subunit binding;
المكونات الخلوية	• photoreceptor inner segment; • غشاء; • photoreceptor outer segment; • photoreceptor disc membrane; • heterotrimeric G-protein complex; • غشاء خلوي; • G-protein beta/gamma-subunit complex;
العمليات الحيوية	• phototransduction; • protein localization; • cardiac muscle cell apoptotic process; • cellular response to hypoxia; • rhodopsin mediated signaling pathway; • eye photoreceptor cell development; • توصيل الإشارة; • G-protein coupled receptor signaling pathway;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	P63211
	Q61012
	‏NM_001329426 NM_021955، ‏NM_001329426
	‏XM_006504986، ‏XM_017321387، ‏XM_017321388، ‏XM_017321389 NM_010314، ‏XM_006504986، ‏XM_017321387، ‏XM_017321388، ‏XM_017321389
	‏NP_068774 NP_001316355، ‏NP_068774
	‏XP_006505049، ‏XP_017176876، ‏XP_017176877، ‏XP_017176878 NP_034444، ‏XP_006505049، ‏XP_017176876، ‏XP_017176877، ‏XP_017176878
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

GNGT1‏ (G protein subunit gamma transducin 1) هوَ بروتين يُشَفر بواسطة جين GNGT1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ Scherer SW, Feinstein DS, Oliveira L, Tsui LC, Pittler SJ (Sep 1996). "Gene structure and chromosome localization to 7q21.3 of the human rod photoreceptor transducin gamma-subunit gene (GNGT1)". Genomics. 35 (1): 241–3. doi:10.1006/geno.1996.0346. PMID 8661128.
^ "Entrez Gene: GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1". مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

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Tao L, Pandey S, Simon MI, Fong HK (1993). "Structure of the bovine transducin gamma subunit gene and analysis of promoter function in transgenic mice". Exp. Eye Res. 56 (4): 497–507. doi:10.1006/exer.1993.1063. PMID 8500562.
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Hinrichs MV, Montecino M, Bunster M, Olate J (2005). "Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate". J. Cell. Biochem. 93 (2): 409–17. doi:10.1002/jcb.20193. PMID 15368366.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Gao X, Sadana R, Dessauer CW, Patel TB (2007). "Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits". J. Biol. Chem. 282 (1): 294–302. doi:10.1074/jbc.M607522200. PMID 17110384.
Seo M, Lee MJ, Heo JH, et al. (2007). "G Protein betagamma subunits augment UVB-induced apoptosis by stimulating the release of soluble heparin-binding epidermal growth factor from human keratinocytes". J. Biol. Chem. 282 (34): 24720–30. doi:10.1074/jbc.M702343200. PMID 17548351.