CKAP2

CKAP2
المعهدات
الأسماء المستعارة	CKAP2, LB1, TMAP, se20-10, cytoskeleton associated protein 2
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 611569 MGI: MGI:1931797 HomoloGene: 10070 GeneCards: 26586
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	Q8WWK9
	Q3V1H1
	‏NM_001098525، ‏NM_001286686، ‏NM_001286687، ‏NM_018204، ‏XM_005266344 XM_011535043، ‏NM_001098525، ‏NM_001286686، ‏NM_001286687، ‏NM_018204، ‏XM_005266344
	‏XM_006509226 NM_001004140، ‏XM_006509226
	‏NP_001273615، ‏NP_001273616، ‏NP_060674، ‏XP_005266401، ‏XP_011533345 NP_001091995، ‏NP_001273615، ‏NP_001273616، ‏NP_060674، ‏XP_005266401، ‏XP_011533345
	‏XP_006509289 NP_001004140، ‏XP_006509289
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

CKAP2‏ (Cytoskeleton associated protein 2) هوَ بروتين يُشَفر بواسطة جين CKAP2 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ "Entrez Gene: CKAP2 cytoskeleton associated protein 2". مؤرشف من الأصل في 05 ديسمبر 2010.
^ Maouche-Chretien L, Deleu N, Badoual C, Fraissignes P, Berger R, Gaulard P, Romeo PH, Leroy-Viard K (Oct 1998). "Identification of a novel cDNA, encoding a cytoskeletal associated protein, differentially expressed in diffuse large B cell lymphomas". Oncogene. 17 (10): 1245–51. doi:10.1038/sj.onc.1202048. PMID 9771967.

قراءة متعمقة

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Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Udina IG, Baranova AV, Kompaniĭtsev AA, Sulimova GE (2001). "[Evolutionarily-conserved gene CKAP2,located in region 13q14.3 of the human genome, is frequently rearranged in various tumors]". Genetika. 37 (1): 120–3. PMID 11234418.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Rakhmanaliev ER, Klimov EA, Kompaniĭtsev AA, Sulimova GE (2003). "[The structure of the human oncogenesis-associated CKAP2 (LB1) gene]". Mol. Biol. (Mosk.). 36 (6): 985–9. PMID 12500535.
Bae CD, Sung YS, Jeon SM, et al. (2004). "Up-regulation of cytoskeletal-associated protein 2 in primary human gastric adenocarcinomas". J. Cancer Res. Clin. Oncol. 129 (11): 621–30. doi:10.1007/s00432-003-0484-0. PMID 12942315.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
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Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Jeon SM, Choi B, Hong KU, et al. (2006). "A cytoskeleton-associated protein, TMAP/CKAP2, is involved in the proliferation of human foreskin fibroblasts". Biochem. Biophys. Res. Commun. 348 (1): 222–8. doi:10.1016/j.bbrc.2006.07.046. PMID 16876122.
Hong KU, Park YS, Seong YS, et al. (2007). "Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis". Mol. Cell. Biol. 27 (10): 3667–81. doi:10.1128/MCB.01386-06. PMC 1900002. PMID 17339342.
Seki A, Fang G (2007). "CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit". J. Biol. Chem. 282 (20): 15103–13. doi:10.1074/jbc.M701688200. PMID 17376772.