GBP1

GBP1
التراكيب المتوفرة
بنك بيانات البروتين	Human UniProt search: PDBe RCSB
قائمة رموز معهدات بنك بيانات البروتين
	1DG3, 1F5N, 2B8W, 2B92, 2BC9, 2D4H
المعهدات
الأسماء المستعارة	GBP1, guanylate binding protein 1
معهدات خارجية	الوراثة المندلية البشرية عبر الإنترنت 600411 HomoloGene: 133759 GeneCards: 2633
فهم الوجود الجيني
الوظيفة الجزيئية	• nucleotide binding; • Hsp90 protein binding; • spectrin binding; • ‏GO:0001948 ربط بروتيني; • identical protein binding; • enzyme binding; • actin binding; • نشاط هيدرولاز; • cytokine binding; • GTPase activity; • GTP binding; • GDP binding; • protein homodimerization activity;
المكونات الخلوية	• عصارة خلوية; • غشاء; • Golgi membrane; • غشاء خلوي; • منطقة خارج الخلية; • سيتوبلازم; • جهاز غولجي; • vesicle membrane; • actin cytoskeleton; • حويصلة سيتوبلازمية;
العمليات الحيوية	• negative regulation of interleukin-2 secretion; • immune system process; • interferon-gamma-mediated signaling pathway; • negative regulation of T cell receptor signaling pathway; • negative regulation of protein localization to plasma membrane; • defense response to virus; • regulation of calcium-mediated signaling; • negative regulation of ERK1 and ERK2 cascade; • negative regulation of substrate adhesion-dependent cell spreading; • regulation of protein localization to plasma membrane; • protein homooligomerization; • cellular response to interferon-gamma; • cellular response to interleukin-1; • cellular response to tumor necrosis factor; • protein localization to vacuole;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	; ;
	المزيد من بيانات التعبير المرجعية
أورثولوج
	P32455
	n/a
	‏XM_024446351 NM_002053، ‏XM_024446351
	‏XM_006233425، ‏XM_008761538، ‏XM_017591353 XM_006224278، ‏XM_006233425، ‏XM_008761538، ‏XM_017591353
	‏XP_024302119 NP_002044، ‏XP_024302119
	n/a
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

GBP1‏ (Guanylate binding protein 1) هوَ بروتين يُشَفر بواسطة جين GBP1 في الإنسان.

الوظيفة

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أوغير مكتمل، ساهم بتحريره.

المراجع

^ Strehlow I, Lohmann-Matthes ML, Decker T (Aug 1994). "The interferon-inducible GBP1 gene: structure and mapping to human chromosome 1". Gene. 144 (2): 295–9. doi:10.1016/0378-1119(94)90393-X. PMID 7518790.
^ "Entrez Gene: GBP1 guanylate binding protein 1, interferon-inducible, 67kDa". مؤرشف من الأصل في 05 ديسمبر 2010.
^ Praefcke GJ, McMahon HT (February 2004). "The dynamin superfamily: universal membrane tubulation and fission molecules?". Nat. Rev. Mol. Cell Biol. 5 (2): 133–47. doi:10.1038/nrm1313. PMID 15040446.

قراءة متعمقة

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